Diflucan - effective drug against most known species of yeast and mold funguses, dermatophytes (that affect hair, horny layer of the epidermis and nails) and dimorphic fungi that can grow in moldy and yeast form. The active substance of Diflucan - Fluconazole has an ability to suppress sterol synthesis in fungal cells, required for the formation of cell membranes.
Indications for use:
Diflucan is prescribed in following cases:
• cryptococcosis, such as cryptococcal meningitis and infections of other sites;
• immunocompromised patients relapse prevention of cryptococcosis;
• generalized candidiasis (thrush damage internal organs);
• mucosal candidiasis;
• acute and recurrent vaginal candidiasis;
• genital candidiasis;
• fungal infections' prevention of patients with malignant tumors whom radiotherapy and cytotoxic chemotherapy may trigger the development of such infections;
• skin fungal infections of different localization ( diseases caused by parasitic fungi);
• deep endemic mycosis (having particular geographical distribution).
Instructions for use:
Cryptococcal infection , cryptococcal meningitis and invasive candida infection is treated by administration of 400 mg of diflucan in the first day and 200-400 mg on subsequent days. Diflucan is used for yeast infections of the oral mucosa, gums, cheeks, tongue, pharynx within 1-2 weeks in amount of 50-100 mg daily. For yeast infection that attacks the vagina, is assigned a single dose of Diflucan in amount of 150 mg. For the skin infections and pityriasis versicolor is recommended to take 50 mg of fluconazole daily for 2-4 weeks; tinea pedis require longer treatment - about 6 weeks. Cryptococcal infection and generalized candidiasis suggest the use of 6-12 mg/kg of Diflucan per day.